Jingbo Liu, ‘Tang Aoqing’ Distinguished Professor of Jilin Uinversity, deputy director of Teaching Guidance committee of the Food Science and Engineering Specialty of the Ministry of Education (2018-2022), member of the Certification conclusions Review Committee of the China Engineering Education Professional certification Association, member of the Food Professional Certification Committee, vice chairman of Asian Egg Association and Egg Processing Branch of China Animal Product Processing Research Institute, director of Functional Food Engineering Research Center and Key Laboratory of Nutrition and Functional Food at Jilin province.
Dr. Liu specializes in the areas of nutrition and functional foods, utilization of egg and byproducts derived from deep processing. Her ongoing and accomplished researches were funded by the National Key R&D Programmes of China (1 project), State Natural Sciences Foundation (3 projects), and by the Ministry of Education of China (1 project). She has published more than 200 papers. Dr. Liu has applied for 90 patents, 39 of which were licensed and 4 of which have been commercialized. Two of her academic projects won the first and second prize in Jilin province. Another six scientific projects were certificated as Achievements of Jilin province.
E-mail: ljb168@sohu.com
Research Interest:
Nutrition and functional foods, especially different kinds of food derived bioactive peptides regarding their preparation, purification, characterization, bioactivity evaluation (through chemical methods, cell culture and animal models to understand the links to health) and industrial application.
Education:
09/2001-06/2004 B.E., Ph.D in College of Biological and Agricultural Engineering Jilin University, Changchun, P.R China
09/1980-07/1984 B.S.A in Animal nutrition, Jilin Agricultural University, Changchun, P.R China
Selected Research Program：
1. The endocytosis mechanism of deoxycholic acid conjugated chitosan-egg white bioactive peptide nanoparticles mediated by ASBT in enterocytes (National Natural Science foundation of China 32072238 2021.01-2024.12)
2. Research and development of key technologies for instant nutritional egg products by green-processing (National Key R&D Program of China 2018YFD0400300 2018.07-2020.12)
3. Research on the intact transport route and mechanism of egg white-derived oligopeptides in Caco-2 monolayers and everted rat intestinal sacs (National Natural Science foundation of China 31771985 2018.01-2021.12)
4. Research on the synergistic antioxidant effect of egg white smallpeptides via Nrf2/ARE signaling pathway (National Natural Science foundation of China 31471597 2015.01-2018.12)
5. Research on the relationship between structure of egg white peptides and intact absorption with Caco-2 cell monolayers (National Natural Science foundation of China 31271907 2013.01-2016.12)
6. Structure and synergy antioxidant activity of egg white-derived small peptides (Specialized Research Fund for the Doctoral Program of Higher 2014.01-2016.12)
Peer-reviewed articles:
1．Xuanting Liu, Qi Yang, Meng Yang, Zhiyang DU, Chen Wei, Ting Zhang, Boqun Liu, Jingbo Liu* (2021). Ultrasound-assisted Maillard reaction of ovalbumin/xylose: The enhancement of functional properties and its mechanism[J]. Ultrasonics sonochemistry, 73:105477.
2．Jingbo Liu, Jiale Chai, Ting Zhang, Yixin Yuan, Ramesh Kumar Saini, Menglei Xu, Shanle Li, Xiaomin Shang (2021). Phase behavior, thermodynamic and rheological properties of ovalbumin/dextran sulfate: Effect of biopolymer ratio and salt concentration[J]. Food Hydrocolloids, 118:106777.
3．Liying Wang, Long Ding, Chunmei Xue, Sitong Ma, Zhiyang Du, Ting Zhang, Jingbo Liu*(2018). Corn gluten hydrolysate regulates the expressions of antioxidant defense and ROS metabolism relevant genes in H2O2-induced HepG2 cells[J]. Journal of Functional Foods, 42:362-370.
4．Long Ding, Liying Wang, Ting Zhang, Zhipeng Yu, Jingbo Liu*(2018). Hydrolysis and transepithelial transport of two corn gluten derived bioactive peptides in human Caco-2 cell monolayers[J]. Food Research International, 106:475-480.
5．Yali Yu, Yao Wang, Ying Wang, Dingbo Lin, Xinxin Li, Jingbo Liu* (2018). Preparation and Properties of Granular Cold-Water-Soluble Maize Starch by Ultrasonic-Assisted Alcoholic-Alkaline Treatment[J]. Starch Biosynthesis, Nutrition, Biomedical, 70:11-12.
6．Long Ding, Liying Wang, Zhipeng Yu, Sitong Ma, Zhiyang Du, Ting Zhang, Jingbo Liu*(2017) Importance of Terminal Amino Acid Residues to the Transport of Oligopeptides across the Caco-2 Cell Monolayer[J]. Journal of Agricultural & Food Chemistry, 65(35):7705.
7．Di Liu, Ting Zhang, Zhifei Chen, Ying Wang, Shuang Ma, Jiyun Liu, Jingbo Liu*(2017). The beneficial effect of ginsenosides extracted by pulsed electric field against hydrogen peroxide-induced oxidative stress in HEK-293 cells[J]. Journal of ginseng research, 41(2): 169-179.
8．Deju Zhang, Yizhen Wang, Menglei Xu, Long Ding, Ting Zhang, Jingbo Liu*(2017). Antioxidant Synergetic Effect Between the Peptides Derived from the Egg White Pentapeptide Trp-Asn-Trp-Ala-Asp[J]. International Journal of Peptide Research & Therapeutics, (8):1-10.
9．Liying Wang, Long Ding, Zhipeng Yu, Ting Zhang, Shuang Ma, Jingbo Liu*. (2016). Intracellular ROS scavenging and antioxidant enzyme regulating capacities of corn gluten meal-derived antioxidant peptides in HepG2 cells. Food Research International.2016
10．Zhipeng Yu, Wenzhu Zhao, Long Ding, Yaqi Wang, Feng Chen, Jingbo Liu*(2016). Short- and Long-term Antihypertensive Effect of egg protein-derived Peptide QIGLF.Journal of The Science of Food and Agriculture, 97(2):551-555.
11．Long Ding, Liying Wang, Zhipeng Yu, Ting Zhang, Jingbo Liu*(2016). Digestionand absorption of an egg white ACE-inhibitory peptide in human intestinal Caco-2 cell monolayers. International Journal of Food Sciences and Nutrition, 67(2):111-116.
12．Zhipeng Yu, Wenzhu Zhao, Long Ding, Yiding Yu, Jingbo Liu*(2016). Anxioly tic eects of ACE inhibitory peptides on the behavior of rats in an elevated plus-maze. Food & Function, 7(1):491-497.
13．Long Ding, Liying Wang, Yan Zhang, Jingbo Liu*(2015). Transport of Antihypertensive Peptide RVPSL, Ovotransferrin 328-332, in Human Intestinal Caco-2 Cell Monolayers [J]. Journal of Agricultural & Food Chemistry, 63(37):8143-8150.
14．Fengguang Pan, Lu Han, Yan Zhang, Yiding Yu, Jingbo Liu*(2015). Optimization of Caco-2 and HT29 co-culture in vitro cell models for permeability studies [J]. International Journal of Food Sciences & Nutrition, 66(6):680-685.
15．Jingbo Liu, Yan Jin, Songyi Lin*, Gregory S. Jones, Feng Chen (2015). Purification and identification of novel antioxidant peptides from egg white protein and their antioxidant activities[J]. Food Chemistry, 175(9):258-266.
16．Ting Zhang, Shaoping Nie, Boqun Liu, Yiding Yu, Yan Zhang, Jingbo Liu* (2015). Activity prediction and molecular mechanism of bovine blood derived angiotensin I-converting enzyme inhibitory peptides. PloS one, 10 (3): e0119598.
17．Liying Wang, Long Ding, Ying Wang, Yan Zhang, Jingbo Liu* (2015). Isolation and Characterisation of in Vitro and Cellular Free Radical Scavenging Peptides from Corn Peptide Fractions. Molecules, 20(2): 3221-3237.
18．Jingbo Liu, Zhifei Chen, Jing He, Yan Zhang, Ting Zhang and Yiqun Jiang (2014). Anti-oxidative and Anti-apoptosis Effects of Egg White Peptide, Trp-Asn-Trp-Ala-Asp, Against H2O2-Induced Oxidative Stress in Human Embryonic Kidney 293 Cells[J]. Food & Function, 5,3179-3188.
19．Long Ding, Yan Zhang, Yiqun Jiang, Liying Wang, Boqun Liu, Jingbo Liu*(2014). Transport of Egg White ACE-Inhibitory Peptide, Gln-Ile-Gly-Leu-Phe, in Human Intestinal Caco 2 Cell Monolayers with Cytoprotective Efffect[J]. Journal of Agricultural and Food Chemsitry, 62, 3177-3182.
20．Zhipeng Yu, Yongguang Yin, Wenzhu Zhao, Feng Chen, Jingbo Liu*(2014). Antihypertensive Effect of Angiotensin-Converting Enzyme Inhibitory Peptide RVPSL on Spontaneously Hypertensive Rats by Regulating Gene Expression of the Renin-Angiotensin System, Journal of Agricultural and Food Chemistry, 62(4): 912-917.
21．Zhipeng Yu, Yongguang Yin, Wenzhu Zhao, Feng Chenb and Jingbo Liu*(2014). Application and bioactive properties of proteins and peptides derived fromhen eggs: opportunities and challenges. J Sci Food Agric, 94: 2839-2845.
22．Zhipeng Yu, Yongguang Yin, Wenzhu Zhao, Jingbo Liu*, Feng Chen (2012). “Anti-diabetic activity peptides from albumin against a-glucosidase and a-amylase”. Food Chemistry:135, 2078–2085.
23．Zhipeng Yu, Boqun Liu, Wenzhu Zhao, Yongguang Yin, Jingbo Liu*, Feng Chen (2012). Primary and secondary structure of novel ACE-inhibitory peptides from egg white protein[J]. Food Chemistry:133: 315-322.
24．Wenzhu Zhao, Yongguang Yin, Zhipeng Yu, Jingbo Liu*, Feng Chen (2012). Comparison of anti-diabetic effects of polysaccharides from corn silk on normal and hyperglycemia rats[J]. International Journal of Biological Macromolecules, 50(4):1133-1137.
25． Songyi Lin, LiyanWang, Gregory Jones, Hung Trang, Yongguang Yin, Jingbo Liu* (2012). Optimized extraction of calcium malate from eggshell treated by PEF and an absorption assessment in vitro[J]. International Journal of Biological Macromolecules:50：1327–1333.
26．Songyi Lin, Yang Guo, Qi You, Yongguang Yin and Jingbo Liu* (2012). Preparation of antioxidant peptide from egg white protein and improvement of its activities assisted by high-intensity pulsed electric field[J]. Journal of the Science of Food and Agriculture, 92: 1554–1561.
27．Minwei Zhang, Hong Ping, Xianyi Cao, Hongkun Li, Fengrui Guan, Chunyan Sun*, Jingbo Liu*(2012). Rapid determination of melamine in milk using water-soluble CdTe quantum dots as fluorescence probes [J]. Food Addit Contam Part A Chem Anal Control Expo Risk Assess, 29(3):333-44.
28．Zhipeng Yu, Wenzhu Zhao, Jingbo Liu*, Jing Lu, Feng Chen (2011). QIGLF, a novel angiotensin I-converting enzyme-inhibitory peptide from egg white protein[J]. Journal of the Science of Food and Agriculture 91(5): 921-926.
29．Wenzhu Zhao, Zhipeng Yu, Jingbo Liu*, Yiding Yu, Yongguang Yin, Songyi Lin, Feng Chen (2011). Optimized extraction of polysaccharides from corn silk by pulsed electric field and response surface quadratic design[J]. Journal of the Science of Food and Agriculture 91(12): 2201-2209.
30．Zhipeng Yu, Yongguang Yin, Wenzhu Zhao, Fei Wang, Boqun Liu, Jingbo Liu*, Feng Chen. (2011). Characterization of ACE-Inhibitory Peptide Associated with Antioxidant and Anticoagulation Properties[J]. Journal of Food Science 76(8): C1149-C1155.
31．Jun Liu, Cuina Wang, Zuozhao Wang, Cheng Zhang, Shuang Lu, Jingbo Liu*(2011). The antioxidant and free-radical scavenging activities of extract and fractions from corn silk (Zea mays L.) and related flavone glycosides[J]. Food Chemistry 126(1): 261-269.
32．Cuina Wang, Tiehua Zhang, Jun Liu, Shuang Lu, Cheng Zhang, Erlei Wang, Zuozhao Wang, Yan Zhang, Jingbo Liu*(2011). Subchronic toxicity study of corn silk with rats[J]. Journal of Ethnopharmacology, 137(1): 36-43.
33． Jun Liu, Songyi Lin, Zuozhao Wang, Cuina Wang, Erlei Wang, Yan Zhang, Jingbo Liu*(2011). Supercritical fluid extraction of flavonoids from Maydis stigma and its nitrite-scavenging ability[J]. Food and Bioproducts Processing, 89(4):333-339.
34．Zhipeng Yu, Yongguang Yin, Wenzhu Zhao, Yiding Yu, Boqun Liu, Jingbo Liu*, Feng Chen (2011). Novel peptides derived from egg white protein inhibiting alpha-glucosidase[J]. Food Chemistry, 129(4):1376-1382.
35．Shuang Guan, Jing Lu, Xue Shen, Wenhui Qian, Jingbo Liu*, Xuming Deng(2011). Florfenicol impairs the immune responses to vaccination against foot-and-mouth disease in mice[J]. Immunopharmacology and Immunotoxicology 33(4): 609-613.
36．Jingbo Liu, Zhipeng Yu*, Wenzhu Zhao, Songyi Lin, Erlei Wang, Yan Zhang, Hui Hao, Zuozhao Wang, Feng Chen (2010). Isolation and identification of angiotensin-converting enzyme inhibitory peptides from egg white protein hydrolysates[J]. Food Chemistry 122(4): 1159-1163.
